M A T E R I A L S A F E T Y D A T A S H E E T E Q U A L- NUTRA SWEET
Product Number: 858900
Product Name: L-Aspartyl-L-phenylalanine methyl ester, 96%
Description / Pricing
Cert. of Analysis
MSDS
Valid 02/2000 - 04/2000
Aldrich Chemical Co., Inc.
1001 West St. Paul
Milwaukee, WI 53233 USA
Tel: 414-273-3850
M A T E R I A L S A F E T Y D A T A S H E E T
SECTION 1. - - - - - - - - - CHEMICAL IDENTIFICATION- - - -
CATALOG #: 858900
NAME: L-ASPARTYL-L-PHENYLALANINE METHYL ESTER, 96%
SECTION 2. - - - - - COMPOSITION/INFORMATION ON INGREDIENTS
CAS #: 22839-47-0
MF: C14H18N2O5
EC NO: 245-261-3 SYNONYMS
3-AMINO-N-(ALPHA- CARBOXYPHENETHYL)SUCCINAMIC ACID N-METHYL ESTER,
STEREOISOMER * ASPARTAME * ASPARTYLPHENYLALANINE METHYL ESTER * N-L-
ALPHA-ASPARTYL-L-PHENYLALANINE 1-METHYL ESTER * CANDEREL * DIPEPTIDE
SWEETENER * EQUAL * METHYL ASPARTYLPHENYLALANATE * 1-METHYL
N-L- ALPHA-
ASPARTYL-L-PHENYLALANINE * NUTRASWEET * L-PHENYLALANINE, N-L-ALPHA-
ASPARTYL-, 1-METHYL ESTER (9CI) * SWEET DIPEPTIDE *
SECTION 3. - - - - - - - - - - HAZARDS IDENTIFICATION - - - - - - -
LABEL PRECAUTIONARY STATEMENTS
HARMFUL
POSSIBLE SENSITIZER.
WEAR SUITABLE PROTECTIVE CLOTHING.
SECTION 4. - - - - - - - - - - FIRST-AID MEASURES- - - - - - - - -
IN CASE OF CONTACT, IMMEDIATELY FLUSH EYES WITH COPIOUS OF AMOUNTS WATER
FOR AT LEAST 15 MINUTES. IN CASE OF CONTACT, IMMEDIATELY WASH SKIN WITH
SOAP AND COPIOUS AMOUNTS OF WATER.
IF INHALED, REMOVE TO FRESH AIR. IF NOT BREATHING GIVE ARTIFICIAL
RESPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
IF SWALLOWED, WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL A PHYSICIAN. WASH CONTAMINATED CLOTHING BEFORE REUSE.
SECTION 5. - - - - - - - - - FIRE FIGHTING MEASURES - - - - - - - -
EXTINGUISHING MEDIA
WATER SPRAY.
CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE FOAM.
SPECIAL FIREFIGHTING PROCEDURES
WEAR SELF-CONTAINED BREATHING APPARATUS AND PROTECTIVE CLOTHING TO
PREVENT CONTACT WITH SKIN AND EYES.
UNUSUAL FIRE AND EXPLOSIONS HAZARDS
EMITS TOXIC FUMES UNDER FIRE CONDITIONS.
SECTION 6. - - - - - - - - ACCIDENTAL RELEASE MEASURES- - - - - - -
WEAR RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER
GLOVES. SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE DISPOSAL. AVOID
RAISING DUST. VENTILATE AREA AND WASH SPILL SITE AFTER MATERIAL PICKUP IS
COMPLETE.
SECTION 7. - - - - - - - - - - HANDLING AND STORAGE- - - - - - - -
REFER TO SECTION 8.
SECTION 8. - - - - - - EXPOSURE CONTROLS/PERSONAL PROTECTION- - - -
CHEMICAL SAFETY GOGGLES.
COMPATIBLE CHEMICAL-RESISTANT GLOVES.
NIOSH/MSHA-APPROVED RESPIRATOR.
SAFETY SHOWER AND EYE BATH.
MECHANICAL EXHAUST REQUIRED.
AVOID INHALATION.
AVOID CONTACT WITH EYES, SKIN AND CLOTHING.
AVOID PROLONGED OR REPEATED EXPOSURE.
WASH THOROUGHLY AFTER HANDLING.
POSSIBLE SENSITIZER.
KEEP TIGHTLY CLOSED.
STORE IN A COOL DRY PLACE.
SECTION 9. - - - - - - - PHYSICAL AND CHEMICAL PROPERTIES - - - - -
APPEARANCE AND ODOR
WHITE POWDER
PHYSICAL PROPERTIES
MELTING POINT: 248 C TO 250 C
SECTION 10. - - - - - - - - -STABILITY AND REACTIVITY - - - - -
- INCOMPATIBILITIES
STRONG OXIDIZING AGENTS
HAZARDOUS COMBUSTION OR DECOMPOSITION PRODUCTS
TOXIC FUMES OF:
CARBON MONOXIDE, CARBON DIOXIDE
NITROGEN OXIDES
SECTION 11. - - - - - - - - - TOXICOLOGICAL INFORMATION - - - - - -
ACUTE EFFECTS
MAY BE HARMFUL BY INHALATION, INGESTION, OR SKIN ABSORPTION.
MAY CAUSE EYE IRRITATION.
MAY CAUSE SKIN IRRITATION.
PROLONGED OR REPEATED EXPOSURE MAY CAUSE ALLERGIC REACTIONS IN
CERTAIN SENSITIVE INDIVIDUALS.
TO THE BEST OF OUR KNOWLEDGE, THE CHEMICAL, PHYSICAL, AND TOXICOLOGICAL
PROPERTIES HAVE NOT BEEN THOROUGHLY
INVESTIGATED.
ADDITIONAL INFORMATION
WARNING TO PERSONS WITH PHENYLKETONURIA! THIS MATERIAL CAN RELEASE
PHENYLALANINE.
RTECS #: WM3407000
SUCCINAMIC ACID, 3-AMINO-N-(ALPHA-CARBOXYPHENETHYL)-, N-METHYL ESTER,
STEREOISOMER
TOXICITY DATA
ORL-RAT LD50:>10 GM/KG TOVEFN (3),37,1996
IPR-RAT LD50:>5 GM/KG TOVEFN (3),37,1996
ORL-MUS LD50:>10 GM/KG TOVEFN (3),37,1996
IPR-MUS LD50:>5 GM/KG TOVEFN (3),37,1996
TARGET ORGAN DATA
SKIN AND APPENDAGES (AFTER SYSTEMIC EXPOSURE: DERMATITIS, ALLERGIC)
ONLY SELECTED REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES
RTECS) DATA IS PRESENTED HERE. SEE ACTUAL ENTRY IN RTECS FOR COMPLETE
INFORMATION.
SECTION 12. - - - - - - - - - ECOLOGICAL INFORMATION - - - - - - -
DATA NOT YET AVAILABLE.
SECTION 13. - - - - - - - - - DISPOSAL CONSIDERATIONS - - - - - - -
DISSOLVE OR MIX THE MATERIAL WITH A COMBUSTIBLE SOLVENT AND BURN IN A
CHEMICAL INCINERATOR EQUIPPED WITH AN AFTERBURNER AND SCRUBBER.
OBSERVE ALL FEDERAL, STATE AND LOCAL ENVIRONMENTAL REGULATIONS.
SECTION 14. - - - - - - - - - - TRANSPORT INFORMATION - - - - - - -
CONTACT ALDRICH CHEMICAL COMPANY FOR TRANSPORTATION INFORMATION.
SECTION 15. - - - - - - - - - REGULATORY INFORMATION - - - - - - -
EUROPEAN INFORMATION HARMFUL
S 36
WEAR SUITABLE PROTECTIVE CLOTHING.
REVIEWS, STANDARDS, AND REGULATIONS
OEL=MAK
EPA TSCA SECTION 8(B) CHEMICAL INVENTORY NIOSH ANALYTICAL METHOD, 1994:
ASPARTAME, 5031
NTP CARCINOGENESIS STUDIES; SELECTED, SEPTEMBER 1999
SECTION 16. - - - - - - - - - - OTHER INFORMATION- - - - - - - - -
THE ABOVE INFORMATION IS BELIEVED TO BE CORRECT BUT DOES NOT PURPORT TO
BE ALL INCLUSIVE AND SHALL BE USED ONLY AS A GUIDE. SIGMA, ALDRICH,
FLUKA SHALL NOT BE HELD LIABLE FOR ANY DAMAGE RESULTING FROM HANDLING
OR FROM CONTACT WITH THE ABOVE PRODUCT. SEE REVERSE SIDE OF INVOICE OR
PACKING SLIP FOR ADDITIONAL TERMS AND CONDITIONS OF SALE.
COPYRIGHT 1999 SIGMA-ALDRICH CO.
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